Orillia Downtown Pharmacy
Orillia Downtown Pharmacy is right in the heart of Mississaga Street. An independently owned pharmacy with a knowledgeable team and the full range of services your community deserves.

New pomotions coming soon
We're always adding new services and promotions. Check back soon to see what's available at this location.


Walkin Clinic
Visit Our Onsite Clinic
This location has an onsite walk-in clinic offering physician care right alongside your pharmacy services. No referral needed - book a visit today!
Addition Support
Addiction Treatment Support in Orillia
Pharmabest Orillia offers confidential, evidence-based addicition treatment for opioid use disorder and other dependencies. Our certified practitioners are here to help, without judgement.

Manage your prescription
Your prescription, handled.
Submit your info.
Fill out a short form and a member of our team will reach out to handle the details personally. Fast, simple, and done for you.
We take care of everything.
Our team manages the entire process on your behalf — contacting your pharmacy, preparing your refill, or handling the transfer. No calls, no paperwork.
Pick up as usual.
Your medications will be ready and waiting at your nearest Pharmabest location.

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We will reach out shortly.
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More than a pharmacy. Care that fits your life.
Orillia Downtown Pharmacy has been serving the Orillia community with personalized, independently owned care. Our pharmacists take the time to understand your health — your medications, your conditions, and what matters most to you. Whether you need a prescription filled, a medication review, support managing diabetes, immunizations, or help quitting smoking, we're here to make it easy and keep it personal.
Monday
9:00am - 6:00pm
Tuesday
9:00am - 6:00pm
Wednesday
9:00am - 6:00pm
Thursday
9:00am - 6:00pm
Friday
9:00am - 6:00pm
Saturday
10:00am - 2:00pm
Sunday
10:00am - 2:00pm
188 Mississaga St E, Orillia, ON L3V 1V9
(705) 325-4010
(705) 325-8240



